It may be associated with either physical or emotional stress, and can occur at any age, although it is more commonly diagnosed in young adults under 50 years old. Central serous retinopathy 1 central serous retinopathy this material will help you understand central serous retinopathy, its causes, and how it may be treated. Intravitreal bevacizumab for treatment of central serous. It occurs most commonly in young men but can occur in men and women of any age.
In csr the macula becomes separated from the eye tissue behind it, and fluid builds up in the space created. Certainly there appears to be cases where improvement has occurred so it is. A new treatment for chronic central serous retinopathy. The cause of these breaks is unknown, though there has been a cortisol, which has been linked to cscr, is a natural steroid that is released by the body when a person is under stress. Central serous retinopathy csr is typically found in young males.
Central serous chorioretinopathy the american society of. When small breaks occur in the rpe, serous fluid the clear part of blood pools under the retina, causing the retina to swell and lift off the layer below it. Central serous chorioretinopathy csc incidence is estimated at 1 per 10,000,1 affecting predominantly men. Central serous retinopathy csr is an idiopathic disease that primarily affects young white men, 20 to 50 years of age, although it is seen occasionally in older patients, females, and other ethnic groups. Optical coherence tomography angiography compared with. Number, shape, and topography of leakage points in acute type i central serous retinopathy. Csc most often occurs in young and middleaged adults. Central serous is associated with an elevation detachment of the macula due to leakage of fluid from the circulation behind it choroidal circulation. Central serous retinopathy csr is an affliction that can cause vision loss or make objects appear much smaller than they are in actuality. To evaluate selective retina therapy srt as a treatment of acute central serous chorioretinopathy. Introduction central serous chorioretinopathy csc cscr most popularly known as csr central serous retinopathy is a sporadic disease of unknown etiology characterized by blister like serous detachment of neurosensory retina and retinal pigment epithelium rpe in the posterior pole of the eye.
Office testing including photography, oct, and a special dye test called a fluorescein and indocyanine green angiography may be performed at your visit. Central serous chorioretinopathy usually affects just one eye at a time, but both eyes can be affected at the same time. Central serous chorioretinopathy, commonly referred to as. Central serous retinopathy is a disease that causes temporary, but in some cases permanent, blurred vision. Central serous retinopathy crs is an eye disorder characterized by fluid buildup under the retina of the eye. It usually affects one eye, but in rare cases both can be affected. Oral rifampin utilisation for the treatment of chronic multifocal central serous retinopathy. Central serous chorioretinopathy eye center of texas. Incorporating current trials and technology into clinical practice. The purpose of this article is to compare optical coherence tomography angiography octa and indocyanine green angiography icga in patients with central serous chorioretinopathy csc. For patients with central serous chorioretinopathy. Central serous retinopathy associated with topical oral. Jun 07, 2017 central serous retinopathy is an eye condition in which fluid builds up behind the retina and affects your vision. Central serous retinopathy an overview sciencedirect topics.
May 16, 2011 the vitreoretinal surgeon confirms the csr central serous retinopathy diagnosis. Central serous retinopathy csr or central serous chorioretinopathy cscr affects the central area of your retina known as the macula. Fluid can be detected in the macula with a dilated eye examination. Bad eye looks like a giant mountain far from being flat due to the fluid that has pushed it up. Spironolactone in the treatment of central serous chorioretinopathya case series.
Csc is characterized by localized subretinal fluid srf at the posterior pole that typically resolves spontaneously within a few months. Pdf central serous chorioretinopathy csc, the fourth most. Abstract background central serous chorioretinopathy csc is a chorioretinal. Research into the success of treating central serous retinopathy with avastin is scanty, but the drug is so successful in wet age related macular degeneration, diabetes and vein occlusions, that there is every reason to hope it works in central serous retinopathy as well. Sep 25, 2015 i have central serous retinopathy or csr, when fluid builds up under the retina. Current concepts in managing central serous chorioretinopathy. To compare the outcomes of treatment with intravitreal bevacizumab ivb versus observation in central serous chorioretinopathy cscr. Jul 01, 2012 update on central serous chorioretinopathy among other findings, reducefluence and lowdose pdt look promising. Central serous chorioretinopathy csc ranks after agedependent macular degeneration, diabetic retinopathy, and retinal vein occlusion as one of the most common visionthreatening retinopathies, with an annual incidence of 1. Central serous retinopathy csr is an eye disease which causes visual impairment, usually in only one eye. Patients often notice a circular grey patch in their vision. Cscr typically occurs in males in their 20s to 50s who exhibit acute or subacute central vision loss or distortion. There is a documented association with stress and steroid use. Central serous chorioretinopathy is a retinal disorder which affects the macula.
The fluid leaks from the choroid the blood vessel layer under the retina. Central serous chorioretinopathy csc, the fourth most common nonsurgical. The margins of the serous detachment are sloping and merge gradually into the normally attached retina of the posterior pole. Contributing factors to central serous retinopathy include the following. Central serous retinopathy begins for reasons that are not well understood. Guidelines for using verteporfin visudyne in photodynamic therapy for choroidal. Central serous chorioretinopathy cscr is a major cause of vision threat among. This is six times more common in men than women, and most often affects people aged between 20 and 50. Csr is a condition in which fluid collects underneath the retina at the back of the eye. Occasionally, it is associated with a single or multiple serous ped. Central serous retinopathy csr rnib see differently. This case report further contributes to the database of potential risks of corticosteroid use.
The margins of the serous detachment are sloping and merge. The symptoms are loss of sensitivity in dim light, usually in an oval shaped gray or brown area, and blurring or distortion of the vision. Ophthalmic atlas images by, the university of iowa are licensed under a creative commons attributionnoncommercialnoderivs 3. Central serous chorioretinopathy, commonly referred to as csc, is a condition in which fluid accumulates under the retina, causing a serous fluidfilled detachment and vision loss. It seems to affect more males than females by a 10 to 1 ratio, and more caucasians than any other race. Retinal physician update on central serous chorioretinopathy. Central serous retinopathy information midwest retina. Oral topical corticosteroid gels are widely used in dental medicine. Additional search terms included central serous retinopathy, central serous choroidopathy. Central serous chorioretinopathy central serous chorioretinopathy, commonly referred to as csc, is a condition in which fluid accumulates under the retina, causing a serous fluidfilled detachment and vision loss.
Central serous retinopathy csr is also known as central serous chorioretinopathy or cscr. Halfdose verteporfin photodynamic therapy for acute central serous chorioretinopathy. This results in an elevation of the retina, which affects the vision. Csc, is a condition in which fluid accumulates under the retina, causing a serous fluidfilled. Central serous chorioretinopa thy csc affects roughly 10 men. Csr can cause your vision to be blurred and distorted due to fluid collecting underneath your macula.
A fluorescein angiogram and b optical coherence tomographic oct image of the central macula in a patient with central serous chorioretinopathy and symptoms for 5 months. Central serous retinopathy taylor retina center, raleigh, nc. Jan 30, 2014 central serous chorioretinopathy is a disease that causes fluid to build up under the retina, the back part of the inner eye that sends sight information to the brain. Central serous retinopathy also known as central serous choroidopathy occurs when fluid builds up under the retina. It is most often a temporary condition and can be treated with excellent results. I have a patient with a typical presentation of idiopathic central serous retinopathy. Central serous chorioretinopathy genetic and rare diseases. Central serous chorioretinopathy also referred to as central serous retinopathy, but more appropriately termed a chorioretinopathy is a condition characterized by a serous macular detachment due to a focal disruption in the outer bloodretinal barrier. Jun 18, 2019 central serous chorioretinopathy cscr is a disease in which a serous detachment of the neurosensory retina occurs over an area of leakage from the choriocapillaris through the retinal pigment epithelium rpe. Comparing imaging capabilities of spectral domain and swept source optical coherence tomography angiography in healthy subjects and central serous retinopathy oct angiography of the choriocapillaris in central serous chorioretinopathy. Central serous chorioretinopathy american society of retina. He then shows me the scans of my good eye and bad eye.
The retina sits ontop of a layer called the choroid, which is what supplies most of the retina with oxygen and nutrients. Combining these facts, the primary hypothesis was that glucocorticoids could. Central serous retinopathy csr is a serious but uncommon reversible condition characterized by fluid accumulation resulting in a localized macular detachment and blurred or distorted central vision. In central serous retinopathy, the fluid is thought to leak from the choroid, a tissue layer under. Central serous retinopathy definition of central serous. Pdf francesco semeraro,1 francesco morescalchi,1 andrea russo,1 elena gambicorti,1 andrea pilotto,2 francesco parmeggiani,3 silvia bartollino,4 ciro. It is a common ocular disease characterized by decompensation of the retinal pigment epithelium rpe, which results in neurosensory retinal detachment, serous pigment epithelium. For unknown reasons, men develop this condition more commonly than women. The average age of onset is the mid30s, but it ranges from the late 20s to late 50s. Serous detachment in the macula in central serous retinopathy. Central serous chorioretinopathy csc primarily affects middleaged men. Central serous retinopathy usually causes typical symptoms. All gvcfs were merged together, and joint genotyping was. Exome sequencing in families with chronic central serous.
Fluoresceinangiographic patterns in patients with central serous chorioretinopathy at the initial visit. Combining the two methods of autofluorescence imaging, swfaf and nirfaf. Central serous retinopathy involves a breakdown of the outer bloodretinal barrier resulting in a localized detachment of the sensory retina in the macula region. Central serous chorioretinopathy cscr, also known as central serous retinopathy or csr, is a condition that usually affects younger people and is characterized by a buildup of fluid underneath the retina. Jul, 2019 central serous retinopathy csr is a retinal condition that affects young to middleaged people with no previous signs or symptoms of retinal disease. Good eye looks like a flat line with a little dip in the middle. The oct section shows a slightly uneven outer profile of the detached retina, with thickening of. A 40yearold south asian woman presented with decreased. The condition is usually unitateral and occurs secondary to retinal pigment epithelial defect. Most reports on central serous retinopathy are prefaced by a summary of the literature, which has now. Central serous chorioretinopathy csc is a disease in which the nsr becomes detached, supposedly due to a single or multiple focal lesions within the rpe, which leaks into the srs overlying dysregulation of the choroidal vasculature. Window defects and latephase leakage from the expanding point in the superior. When to treat and not to treat patients with central serous. Oct angiography of the choriocapillaris in central serous.
In most people, csr gets better on its own and doesnt cause longterm changes to vision. A buildup of fluid results in swelling and raised retinal tissue close to the macula and may result in retinal detachment. Pdf on aug 3, 2015, laura steeples and others published traumatic central serous retinopathy find, read and cite all the research you. This results in blurred vision or poor night vision. The fluid seeps in between layers of the retina and causes them to separate. May 09, 2020 central serous chorioretinopathy csr is a disease marked by painless neurosensory detachment of the macula thought to be related to dysfunction of the outer retina or inner choroid allowing. Central serous retinopathy retina consultants of seattle. Case studies of central serous retinopathy have been reported following administration of corticosteroids, but none so far coinciding with the use of topical fluocinonide gel. Central serous chorioretinopathy csc is a common retina disease and has a. The retina is a thin, sensitive layer of tissue in the back of the eye. Assessment for central serous retinopathy we are able to detect central serous retinopathy during an examination by performing a dilated eye exam. Symptoms of central serous chorioretinopathy can include. Pdf traumatic central serous retinopathy researchgate. Central serous retinopathy csr is a pathologic condition characterized by swelling and elevation of retinal tissue near the macula due to accumulation of fluid between the photoreceptor outer segments and the retinal pigment epithelium rpe, often leading to detachment of the neurosensory retina.
Central serous retinopathy csr, also known as central serous chorioretinopathy csc or cscr, is an eye disease that causes visual impairment, often temporary, usually in one eye. The effects of central serous retinopathy are normally temporary and most patients recover good. Figure 3 early and late fluorescein angiograms of a 29yearold patient affected by chronic central serous chorioretinopathy revealing an irregularity of the retinal pigment epithelium, resembling a honeycomb pattern, near the point of fluorescein leakage. This accumulation is a reason why patients typically complain about problems with their vision in dim light, especially in an oval shaped gray or brown area. Choroidal neovascularization secondary to central serous. Essentially, it is an idiopathic disorder which means that the precise cause is unknown. The condition may be triggered or exacerbated by stress or corticosteroid use. The foveal photoreceptor layer and visual acuity loss in. The retina is the tissue lining the back of the eye that sends vision signals through the optic nerve to the brain. Central serous chorioretinopathy csc is a disorder characterized by serous retinal detachment andor retinal pigment epithelial rpe detachment, changes most often confined to the macula, and associated with leakage of fluid through the rpe into the subretinal space.
604 135 1120 996 1213 85 766 702 361 956 462 1266 42 340 243 1152 1119 764 1209 179 361 318 906 972 1011 489 106 1269 973 622 1166 149 124 994 322 895 167 515 178 1324 1323 384 1229 943 626 1033 647 916